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Acyclovir-5'-monophosphate

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Category Herpes simplex Virus (HSV)
CAS 66341-16-0
Description Acyclovir-5'-monophosphate is a nucleotide analog that has the potential to treat herpes virus infections.
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Product Information

Synonyms 2-Amino-1,9-dihydro-9-[[2-(phosphonooxy)ethoxy]methyl]-6H-purin-6-one; Acycloguanosine Monophosphate
IUPAC Name 2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethyl dihydrogen phosphate
Molecular Weight 305.18 (free acid)
Molecular Formula C8H12N5O6P (free acid)
Canonical SMILES C1=NC2=C(N1COCCOP(=O)(O)O)N=C(NC2=O)N
InChI InChI=1S/C8H12N5O6P/c9-8-11-6-5(7(14)12-8)10-3-13(6)4-18-1-2-19-20(15,16)17/h3H,1-2,4H2,(H2,15,16,17)(H3,9,11,12,14)
InChIKey KUOAJOVOKFATQE-UHFFFAOYSA-N
Boiling Point 716.0±70.0 °C at 760 mmHg
Melting Point >182°C (dec.)
Flash Point 386.8±35.7 °C
Purity ≥ 95% by HPLC
Density 2.1±0.1 g/cm3
Solubility In vitro:
10 mM in DMSO
Appearance white powder
Application Antiviral Agents
Storage Store at -20°C
Complexity 453
Exact Mass 305.052521
Index Of Refraction 1.780
PSA 175.39000
Target HSV
Vapor Pressure 0.0±2.4 mmHg at 25°C
XLogP3-AA -3

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