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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
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- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
6-Azathymine
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| Category | Influenza Virus |
| CAS | 932-53-6 |
| Description | 6-Azathymine, a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor, inhibits DNA biosynthesis and has antibacterial and antiviral activities. |
Product Information
| Synonyms | 6-Methyl-1,2,4-triazine-3,5(2H,4H)-dione; 5-Methyl-6-azauracil; Azathymine; 6-Methyl-1,2,4-triazine-3,5-diol; 6-Methyl-1,2,4-triazine-3,5-dione; NSC 3426; 6-Methyl-as-triazine-3,5-(2H,4H)-dione; NSC 38620; 3,5-Dihydroxy-6-methyl-1,2,4-triazine |
| IUPAC Name | 6-methyl-2H-1,2,4-triazine-3,5-dione |
| Molecular Weight | 127.10 |
| Molecular Formula | C4H5N3O2 |
| Canonical SMILES | CC1=NNC(=O)NC1=O |
| InChI | InChI=1S/C4H5N3O2/c1-2-3(8)5-4(9)7-6-2/h1H3,(H2,5,7,8,9) |
| InChIKey | XZWMZFQOHTWGQE-UHFFFAOYSA-N |
| Melting Point | 210-212°C |
| Purity | ≥95% |
| Density | 1.67±0.1 g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid Powder |
| Storage | Store at RT |
| Complexity | 196 |
| Exact Mass | 127.038177 |
| Index Of Refraction | 1.692 |
| In Vitro | 6-Azathymine is a competitive antagonist of the growth of Streptococcus faecalis and several other strains of microorganisms. |
| In Vivo | The administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. |
| PSA | 78.61000 |
| Target | Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Bacterial; Influenza Virus |
| XLogP3-AA | -0.3 |
