4′-C-Fluoro-2′-C-methyluridine

Category	Hepatitis C Virus (HCV)
CAS	1613589-04-0
Description	4'-C-Fluoro-2'-C-methyluridine is a modified form of uridine where the oxygen at the 2' position of the ribose sugar is replaced by a methyl group, and a fluorine atom is attached to the carbon at the 4' position of the ribose sugar. This modification enhances the stability and binding affinity of the nucleotide, making it useful in various molecular biology applications, including RNA structure studies, antisense oligonucleotide design, and as a substrate for enzymatic reactions in RNA biochemistry research.

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Synonyms	1613589-04-0;1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione;Adafosbuvir PM;SCHEMBL15817679;Uridine, 4'-C-fluoro-2'-C-methyl-;TS-09379;1-((2R,3R,4S,5S)-5-Fluoro-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione;
IUPAC Name	1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione
Molecular Weight	276.22
Molecular Formula	C10H13FN2O6
Canonical SMILES	O[C@]1(C)[C@H](O)[C@](CO)(F)O[C@H]1N2C(NC(C=C2)=O)=O
InChI	InChI=1S/C10H13FN2O6/c1-9(18)6(16)10(11,4-14)19-7(9)13-3-2-5(15)12-8(13)17/h2-3,6-7,14,16,18H,4H2,1H3,(H,12,15,17)/t6-,7+,9+,10+/m0/s1
InChIKey	NVGHRKFZVNJJFZ-MVHNUAHISA-N
Purity	≥95%
Density	1.68±0.1 g/cm3
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.