3-O-Methylviridicatin

Category	Human immunodeficiency Virus (HIV)
CAS	6152-57-4
Description	O-Methylviridicatin is a metabolite produced by several species of Penicillium. It blocks TNF-alpha activation of the HIV LTR in the Hela-based system, with an IC50 of 5 mM, and inhibits virus production in the OM-10.1 cell line, a model of chronic infection responsive to induction by TNF-alpha, with an IC50 of 2.5 mM.

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Synonyms	3-O-Methylviridicatin;6152-57-4;3-Methoxy-4-phenyl-1H-quinolin-2-one;O-methylviridicatin;3-methoxy-4-phenylquinolin-2(1h)-one;Methylviridicatin, O-;AIDS-089094, 3-Methoxy-4-phenyl-1H-quinolin-2-one;CHEMBL235425;DTXSID30210514;CHEBI:201725;HY-122786;CS-0089351;
IUPAC Name	3-methoxy-4-phenyl-1H-quinolin-2-one
Molecular Weight	366.3
Molecular Formula	C17H18O9
Canonical SMILES	C1=CC=C2C(=C1)C(=CC(=C2O)C(=O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O
InChI	InChI=1S/C16H13NO2/c1-19-15-14(11-7-3-2-4-8-11)12-9-5-6-10-13(12)17-16(15)18/h2-10H,1H3,(H,17,18)
InChIKey	NDTLHHOQSHJIMX-UHFFFAOYSA-N
Boiling Point	476.5°C at 760 mmHg
Melting Point	184.2°C
Purity	≥99%
Density	1.25 g/cm3
Solubility	Soluble in DMSO, DMF, Ethanol, Methanol, Water
Appearance	Solid
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.