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3'-Deoxy-3'-fluorothymidine(ALOVUDINE)

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Category Orthopoxvirus
CAS 25526-93-6
Description It is an antiviral agent, DNA polymerase inhibitor and HIV inhibitor.
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Product Information

Synonyms 2',3'-Dideoxy-3'-fluoro-5-methyluridine; 3'-FddT; Alovudine; CL184824; 3'-Deoxy-3'-fluoro-thymidine; 1-(3'-Deoxy-3'-fluoro-β-D-pentofuranosyl)thymine; 3'-Fluoro-3'-deoxythymidine; 3'-Fluorodeoxythymidine; 3'-Fluorothymidine; FLT; NSC 140025
IUPAC Name 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Molecular Weight 244.22
Molecular Formula C10H13FN2O4
Canonical SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)F
InChI InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1
InChIKey UXCAQJAQSWSNPQ-XLPZGREQSA-N
Melting Point 169-172°C
Purity ≥95%
Density 1.44±0.1 g/cm3
Solubility Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Appearance White to Beige Solid
Application Antiviral Agents
Storage Store at -20°C under inert atmosphere
Exact Mass 88.06880
Target DNA/RNA Synthesis; Orthopoxvirus

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