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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
3'-Deoxy-3'-fluorothymidine(ALOVUDINE)
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| Category | Orthopoxvirus |
| CAS | 25526-93-6 |
| Description | It is an antiviral agent, DNA polymerase inhibitor and HIV inhibitor. |
Product Information
| Synonyms | 2',3'-Dideoxy-3'-fluoro-5-methyluridine; 3'-FddT; Alovudine; CL184824; 3'-Deoxy-3'-fluoro-thymidine; 1-(3'-Deoxy-3'-fluoro-β-D-pentofuranosyl)thymine; 3'-Fluoro-3'-deoxythymidine; 3'-Fluorodeoxythymidine; 3'-Fluorothymidine; FLT; NSC 140025 |
| IUPAC Name | 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione |
| Molecular Weight | 244.22 |
| Molecular Formula | C10H13FN2O4 |
| Canonical SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)F |
| InChI | InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1 |
| InChIKey | UXCAQJAQSWSNPQ-XLPZGREQSA-N |
| Melting Point | 169-172°C |
| Purity | ≥95% |
| Density | 1.44±0.1 g/cm3 |
| Solubility | Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Appearance | White to Beige Solid |
| Application | Antiviral Agents |
| Storage | Store at -20°C under inert atmosphere |
| Exact Mass | 88.06880 |
| Target | DNA/RNA Synthesis; Orthopoxvirus |
