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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
3-Deaza-2'-deoxyadenosine
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| Category | Herpes simplex Virus (HSV) |
| CAS | 78582-17-9 |
| Description | It has a strong inhibitory effect on lymphocyte-mediated cytolysis, but has low cytotoxicity at 100 μM. This nucleoside can also be used to evaluate the role of adenine N3 nitrogen in DNA structure and function. |
Product Information
| Synonyms | 78582-17-9;3-Deaza-2'-deoxyadenosine;(2R,3S,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol;(2R,3S,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-2-(hydroxymethyl)oxolan-3-ol;4-Amino-2-deoxyribofuranosylimidazo[4,5-c]pyridine;2'-Deoxy-3-deazaadenosine;3-Deaza-2/'-deoxyadenosine;(2R,3S,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol;3-Deaza-2'-dA;CHEMBL3143904;SCHEMBL11021787;DTXSID00229178;1H-Imidazo[4,5-c]pyridin-4-amine,1-(2-deoxy-b-D-erythro-pentofuranosyl)-;AKOS026670209;AC-32284;PD019526;1H-Imidazo(4,5-c)pyridin-4-amine, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-;1H-Imidazo[4,5-c]pyridin-4-amine, 1-(2'-deoxy-.beta.-D-erythro-pentofuranosyl)-; |
| IUPAC Name | (2R,3S,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-2-(hydroxymethyl)oxolan-3-ol |
| Molecular Weight | 189.21 |
| Molecular Formula | C10H11N3O |
| Canonical SMILES | CC=CC=NNC(=O)C1=CC=NC=C1 |
| InChI | InChI=1S/C11H14N4O3/c12-11-10-6(1-2-13-11)15(5-14-10)9-3-7(17)8(4-16)18-9/h1-2,5,7-9,16-17H,3-4H2,(H2,12,13)/t7-,8+,9+/m0/s1 |
| InChIKey | KMQPIRJQPAVGJL-DJLDLDEBSA-N |
| Boiling Point | 617.7±65.0°C (Predicted) |
| Melting Point | 208-209°C |
| Purity | ≥97% by HPLC |
| Density | 1.75±0.1 g/cm3 (Predicted) |
| Solubility | Soluble in DMF (5 mg/ml), DMSO (20 mg/ml), PBS (pH 7.2, 10 mg/ml) |
| Appearance | Crystalline Powder |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
