-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
3′-Azido-2′,3′-dideoxyuridine
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 84472-85-5 |
| Description | Navuridine is a RNA-directed DNA polymerase inhibitor under the development of Bayer HealthCare Pharmaceuticals. But research for the teatment of HIV infections was discontinued. |
Product Information
| Synonyms | Navuridine;AZddU;84472-85-5;3'-AZIDO-2',3'-DIDEOXYURIDINE;AZdU;Navuridine [INN];CS-87;Uridine, 3'-azido-2',3'-dideoxy-;NSC-380882;PS28W65479;AzUrd;UNII-PS28W65479;1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione;AZddU & GM-CSF;NAVURIDINE [MART.];CHEMBL591804;3'-azido-2',3'dideoxyuridine;SCHEMBL15531699;ZSNNBSPEFVIUDS-SHYZEUOFSA-;ZSNNBSPEFVIUDS-SHYZEUOFSA-N;DTXSID901004737;MFCD00870324;1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;AKOS040744855;DA-65951;MS-23568;NS00122876;A855471;Uridine, 3'-azido-2',3'-dideoxy- and JPS-783;Q27286725;1-(3-Azido-2,3-dideoxypentofuranosyl)-4-hydroxypyrimidin-2(1H)-one;1-((2R*,4S*,5S*)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione;1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione;3'-Azido-2',3'-dideoxyuridine & Granulocyte-macrophage colony-stimulating factor;InChI=1/C9H11N5O4/c10-13-12-5-3-8(18-6(5)4-15)14-2-1-7(16)11-9(14)17/h1-2,5-6,8,15H,3-4H2,(H,11,16,17)/t5-,6+,8+/m0/s1; |
| IUPAC Name | 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| Molecular Weight | 285.3 |
| Molecular Formula | C15H11NO3S |
| Canonical SMILES | COC(=O)C1=CC=CC=C1N2C(=O)C3=CC=CC=C3S2 |
| InChI | InChI=1S/C9H11N5O4/c10-13-12-5-3-8(18-6(5)4-15)14-2-1-7(16)11-9(14)17/h1-2,5-6,8,15H,3-4H2,(H,11,16,17)/t5-,6+,8+/m0/s1 |
| InChIKey | ZSNNBSPEFVIUDS-SHYZEUOFSA-N |
| Melting Point | 166-168°C |
| Purity | ≥95% |
| Solubility | Soluble in DMSO (Slightly), Methanol (Very Slightly) |
| Appearance | Solid |
| Application | HIV infections |
| Shelf Life | 2 month in rt, long time |
| Storage | Store at -20°C under inert atmosphere |
