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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
3,4'-Dihydroxyflavone
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| Category | Influenza Virus |
| CAS | 14919-49-4 |
| Description | 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus. |
Product Information
| Synonyms | 3,4'-DHF; 3-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 4'-hydroxyflavonol |
| Molecular Weight | 254.24 |
| Molecular Formula | C15H10O4 |
| Canonical SMILES | C1=CC=C2C(=C1)C(=O)C(=C(O2)C3=CC=C(C=C3)O)O |
| InChI | InChI=1S/C15H10O4/c16-10-7-5-9(6-8-10)15-14(18)13(17)11-3-1-2-4-12(11)19-15/h1-8,16,18H |
| InChIKey | GPGOCTLAUAHUQO-UHFFFAOYSA-N |
| Purity | ≥95% |
| Solubility | In Vitro: DMSO: ≥ 155 mg/mL(609.66 mM) |
| Appearance | Solid Powder |
| Storage | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
| Exact Mass | 371.18900 |
| In Vivo | 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death. |
| PSA | 37.38000 |
| Target | Influenza Virus |
