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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
2-Picolinic acid
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| Category | Virus Protease |
| CAS | 98-98-6 |
| Description | Picolinic acid is a metabolite of tryptophan that acts as an anti-infective and immunomodulator. It is produced under inflammatory conditions. |
Product Information
| Synonyms | pyridine-2-carboxylic acid |
| IUPAC Name | pyridine-2-carboxylic acid |
| Molecular Weight | 123.11 |
| Molecular Formula | C6H5NO2 |
| Canonical SMILES | C1=CC=NC(=C1)C(=O)O |
| InChI | InChI=1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9) |
| InChIKey | SIOXPEMLGUPBBT-UHFFFAOYSA-N |
| Boiling Point | 292.5±13.0 °C at 760 mmHg |
| Melting Point | 139-142 ℃ (lit.) |
| Flash Point | 130.7±19.8 °C |
| Purity | 95 % |
| Density | 1.3±0.1 g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Off-white to tan powder |
| Application | Iron Chelating Agents |
| Storage | Store at RT. |
| Complexity | 114 |
| Exact Mass | 123.032028402 |
| Index Of Refraction | 1.571 |
| In Vitro | Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations. |
| PSA | 50.19000 |
| Target | Endogenous Metabolite; Virus Protease |
| Vapor Pressure | 0.0±0.6 mmHg at 25°C |
