2-Picolinic acid

Category	Virus Protease
CAS	98-98-6
Description	Picolinic acid is a metabolite of tryptophan that acts as an anti-infective and immunomodulator. It is produced under inflammatory conditions.

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Synonyms	pyridine-2-carboxylic acid
IUPAC Name	pyridine-2-carboxylic acid
Molecular Weight	123.11
Molecular Formula	C6H5NO2
Canonical SMILES	C1=CC=NC(=C1)C(=O)O
InChI	InChI=1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9)
InChIKey	SIOXPEMLGUPBBT-UHFFFAOYSA-N
Boiling Point	292.5±13.0 °C at 760 mmHg
Melting Point	139-142 °C (lit.)
Flash Point	130.7±19.8 °C
Purity	95 %
Density	1.3±0.1 g/cm3
Solubility	In vitro: 10 mM in DMSO
Appearance	Off-white to tan powder
Application	Iron Chelating Agents
Storage	Store at RT.
Complexity	114
Exact Mass	123.032028402
Index Of Refraction	1.571
In Vitro	Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations.
PSA	50.19000
Target	Endogenous Metabolite; Virus Protease
Vapor Pressure	0.0±0.6 mmHg at 25°C