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2'-O-Methylcytidine

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Category Hepatitis C Virus (HCV)
CAS 2140-72-9
Description Cytidine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.
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Product Information

Synonyms 2'-(O-Methyl) Cytidine; Cytidine, 2'-O-methyl-; 2'-O-Methyl cytidine; O(2')-Methylcytidine; 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 4-Amino-1-(2-O-methyl-β-D-ribofuranosyl)pyrimidin-2(1H)-one
IUPAC Name 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one
Molecular Weight 257.24
Molecular Formula C10H15N3O5
Canonical SMILES COC1C(C(OC1N2C=CC(=NC2=O)N)CO)O
InChI InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
InChIKey RFCQJGFZUQFYRF-ZOQUXTDFSA-N
Boiling Point 506.0±60.0°C (Predicted)
Melting Point >247°C (dec.)
Flash Point 259.8±32.9 °C
Purity ≥95%
Density 1.68±0.1 g/cm3 (Predicted)
Solubility Soluble in DMSO (Slightly), Methanol (Slightly, Heated)
Appearance White Solid
Storage Store at 2-8°C
Exact Mass 257.101166
Index Of Refraction 1.677
PSA 119.83000
Target HCV
Vapor Pressure 0.0±3.0 mmHg at 25°C

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