Required fields are marked with *

Verification code

2'-Deoxy-5'-O-DMT-2'-fluoro-uridine

{PARAM:[Name]}()
Category Influenza Virus
CAS 146954-74-7
Description It is used for RNA synthesis and nucleoside modification.
Quotation Now

Product Information

Synonyms 2'-F-5'-O-DMT-2'-dU; 5'-O-DMT-2'-fluoro-2'-deoxy-D-uridine; 2'-Fluoro-5'-O-DMT-uridine; 2'-Deoxy-5'-O-DMT-2'-fluoro-D-uridine; 5'-O-DMT-2'-fluoro-2'-deoxyuridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-DMTr-2'-F-dU
IUPAC Name 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione
Molecular Weight 548.56
Molecular Formula C30H29FN2O7
Canonical SMILES COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)F)O
InChI InChI=1S/C30H29FN2O7/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-27(35)26(31)28(40-24)33-17-16-25(34)32-29(33)36/h3-17,24,26-28,35H,18H2,1-2H3,(H,32,34,36)/t24-,26-,27-,28-/m1/s1
InChIKey CSSFZSSZXOCCJB-YULOIDQLSA-N
Purity ≥95%
Density 1.38±0.1 g/cm3(Predicted)
Solubility Soluble in DMSO (10 mM)
Appearance White to Off-white Crystalline Powder
Storage Store at -20°C
Complexity 873
Exact Mass 851.34600
In Vitro 2'-Deoxy-5'-O-DMT-2'-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM, and it proves to be noncytotoxic at concen-trations up to 20 mM.
PSA 159.99000
Target Filovirus
XLogP3-AA 3.6

TAKE YOUR NEXT STEPS

Get Started With Our Industry Experience And Client-Centric Focus!

Talk to Us

Copyright © 2024 BOC Sciences. All rights reserved.