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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
2'-Deoxy-2'-fluoroguanosine
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| Category | Influenza Virus |
| CAS | 78842-13-4 |
| Description | It is an influenza viral polymerase inhibitor like Ribavirin, used as an antiviral drug against avian (H5N1) influenza virus. |
Product Information
| Synonyms | 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)guanine; 2'-Fluoro-2'-deoxyguanosine; 2-Amino-9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 2'-deoxy-2'-fluoro-; 2'-Fluoro-Riboguanosine |
| IUPAC Name | 2-amino-9-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one |
| Molecular Weight | 285.23 |
| Molecular Formula | C10H12FN5O4 |
| Canonical SMILES | C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(NC2=O)N |
| InChI | InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4-,6-,9-/m1/s1 |
| InChIKey | UXUZARPLRQRNNX-DXTOWSMRSA-N |
| Melting Point | 262-264°C (water) |
| Purity | ≥95% |
| Density | 2.17±0.1 g/cm3 (Predicted) |
| Solubility | Soluble in Water |
| Appearance | White to Off-white Powder |
| Application | Antiviral Agents |
| Storage | Store at -20°C |
| Exact Mass | 545.04900 |
| PSA | 151.81000 |
| Target | EC90: <0.35 μM (influenza virus A and B) |
