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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
2'-Deoxy-2'-fluoroarabinoadenosine
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 20227-41-2 |
| Description | As an analog of the antitumour and antiviral naturally occurring nucleoside 9-(β-D-arabinofuranosyl)adenine (ara-A), 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine inhibited the growth of T. vaginalis with an IC50 of 0.09μM. |
Product Information
| Synonyms | 20227-41-2;9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)adenine;(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol;arabino-F-Ado;CHEMBL2032002;(2R,3R,4S,5R)-5-(6-AMINOPURIN-9-YL)-4-FLUORO-2-(HYDROXYMETHYL)OXOLAN-3-OL;(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;C10H12FN5O3;SCHEMBL1389499;123334-75-8;BDBM50452569;MFCD12911815;2??-Deoxy-2??-fluoroarabinoadenosine;AKOS027327937;AC-32315;AS-68707;F13969;A855629;2 inverted exclamation mark -Deoxy-2 inverted exclamation mark -fluoroarabinoadenosine;(2R,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol;9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine; |
| IUPAC Name | (2R,3R,4S,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol |
| Molecular Weight | 450.5 |
| Molecular Formula | C26H30N2O5 |
| Canonical SMILES | CC1=C(C(=O)OC2=C1C=CC(=C2)OCC(CN3CCC(CC3)C(=O)N)O)CC4=CC=CC=C4 |
| InChI | InChI=1S/C10H12FN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5+,7-,10-/m1/s1 |
| InChIKey | ZGYYPTJWJBEXBC-GQTRHBFLSA-N |
| Boiling Point | 628.6±65.0 °C at 760 mmHg |
| Melting Point | 233-234 °C |
| Purity | ≥97% by HPLC |
| Density | 2.01±0.1 g/cm3 |
| Solubility | Soluble in DMSO, not in water. |
| Appearance | Solid |
| Application | Anti-neoplastic; Inhibits the growth of T. vaginalis with an IC50 of 0.09μM |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
