Lucidone

Category	Hepatitis B Virus (HBV)
CAS	19956-53-7
Description	Lucidone, coming from the root of Lindera strychnifolia, may possess antioxidant and anti-inflammatory properties and may be useful for the prevention of free radical-induced skin damage. The anti-inflammatory activity of lucidone might cause by the inhibition of iNOS and COX-2 expressions through the down-regulation of NF-κB and AP-1 binding activity. Besides, the effects of lucidone on tyrosinase and antimelanogenic activity were investigated, lucidone strongly inhibits the activity of mushroom tyrosinase. The antimelanogenic activity of lucidone is probably due to its inhibition of tyrosinase activity and the suppression of tyrosinase and MITF expression.

Quotation Now

Synonyms	Lucidone;19956-53-7;3-hydroxy-4-methoxy-2-[(E)-3-phenylprop-2-enoyl]cyclopenta-2,4-dien-1-one;4-Cyclopentene-1,3-dione, 2-(1-hydroxy-3-phenyl-2-propenylidene)-4-methoxy-, (Z,E)-;SCHEMBL6846053;CHEBI:183569;LMPK12120439;AKOS032948482;AKOS040744744;FS-9524;4-Cyclopentene-1,3-dione, 2-[(2E)-1-hydroxy-3-phenyl-2-propenylidene]-4-methoxy-, (2Z)-;DA-65101;(2Z)-2-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-4-methoxycyclopent-4-ene-1,3-dione;4-Cyclopentene-1,3-dione, 2-(-hydroxycinnamylidene)-4-methoxy- (8CI); (2Z)-2-[(2E)-1-Hydroxy-3-phenyl-2-propenylidene]-4-methoxy-4-cyclopentene-1,3-dione;
IUPAC Name	3-hydroxy-4-methoxy-2-[(E)-3-phenylprop-2-enoyl]cyclopenta-2,4-dien-1-one
Molecular Weight	486.7
Molecular Formula	C30H46O5
Canonical SMILES	C[C@@H]1C[C@@H]2[C@H](O[C@]3([C@H]1[C@]4(CC[C@@]56C[C@@]57CCC(=O)C([C@@H]7CC[C@H]6[C@@]4([C@H]3O)C)(C)C)C)O2)C(C)(C)O
InChI	InChI=1S/C15H12O4/c1-19-13-9-12(17)14(15(13)18)11(16)8-7-10-5-3-2-4-6-10/h2-9,18H,1H3/b8-7+
InChIKey	ANPTXNYQLGJVRE-BQYQJAHWSA-N
Boiling Point	489.6±45.0°C (Predicted)
Melting Point	166.5-168.5°C
Purity	>98%
Density	1.30±0.1 g/cm3(Predicted)
Appearance	Solid
Application	Antimelanogenic/antioxidant/anti-inflammatory
Storage	-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)